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Tracy (1990 – 1997) was a transgenically modified sheep created by scientists at Scotland's Roslin Institute to produce the human protein alpha 1-antitrypsin, a substance regarded in the 1990s as a potential pharmaceutical for the treatments of cystic fibrosis and emphysema.〔http://www.sciencemuseum.org.uk/broughttolife/objects/display.aspx?id=6151〕 Notably, she is the first transgenic farm mammal ever created.〔(【引用サイトリンク】url=http://www.aphis.usda.gov/animal_health/emergingissues/downloads/animal_pharming.pdf )〕 Alpha 1-antitrypsin comprised 50% of the total protein in Tracy's milk, a remarkably high level maintained after lactation. Similar levels were detected in the milk produced by her granddaughters. A deficiency in this protein in humans can produce lung diseases, and its artificial creation was thought to be a potential success in the diseases' treatment.〔 Clinical trials for the engineered protein in 1998 revealed that it developed breathing problems in patients, and research for the milk as a remedy for the diseases has not continued since then. ==See also== *Dolly (sheep) *Pharming (genetics) *Genetically modified organisms 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Tracy (sheep)」の詳細全文を読む スポンサード リンク
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